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Research Assistant (TEMPORARY)

Location Novato, California
BioMarin is the world leader in delivering therapeutics that provide meaningful advances to patients who live with serious and life-threatening rare genetic diseases. We target diseases that lack effective therapies and affect relatively small numbers of patients, many of whom are children. These conditions are often inherited, difficult to diagnose, progressively debilitating and have few, if any, treatment options. BioMarin will continue to focus on advancing therapies that are the first or best of their kind.

BioMarin’s Technical Operations group is responsible for creating our drugs for use in clinical trials and for scaling production of those drugs for the commercial market. These engineers, technicians, scientists and support staff build and maintain BioMarin’s cutting-edge manufacturing processes and sites, provide quality assurance and quality control to ensure we meet regulatory standards, and procure the needed goods and services to support manufacturing and coordinating the worldwide movement of our drugs to patients. Come join our team and make a meaningful impact on patients’ lives. 


Primary responsibility is support for the Assay Services subgroup within Analytical Chem. This position involves documentation of samples received for analysis and performance of a variety of analytical assays with adherence to strict timelines. Assays may include enzyme activity, total protein, cell-based bioassays, chromatography and electrophoresis, done under the supervision of more senior personnel.  Assists in the qualification of assay methods and in their transfer to the Quality Control laboratories.  Provides major contributions to the evaluation of drug substance and drug product.  Responsible for operational aspects of the laboratory through ordering, equipment maintenance and organization.

Scope: Data generated is used for lot release and stability evaluation of clinical batches of drug substance and drug product.  Data generated is also used in decisions involving process development/formulation projects. 

Receives, documents sample submission and records results for Assay Services in support of a variety of different groups including QCCS, Cell Culture PD, Purification PD and Formulation.

    • Performs analytical assays for samples within and outside the purview of assay services. Including enzyme activity, total protein by Bradford or A280, cellular uptake bioassays, gel and capillary electrophoresis and HPLC methods. 

    • Under appropriate supervision, assists Research Associates and Scientists in the qualification of assay methods for transfer to the Quality Control Analytical and In-Process laboratories.

    • With increasing experience, develops the capacity to troubleshoot assay methods and to suggest remedies for problems or improvements to the methods.

    • Other duties as assigned.



Describe the work environment characteristics that an employee encounters while performing the essential functions of the job.

The work environment characteristics described here are representative of those an employee encounters while performing the essential functions of this job.  Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.

Primarily a laboratory position; contact with chemicals is part of the job.  The employee will be trained to use common lab equipment and minimize exposure to hazards.   Desktop or laptop computer work is also a major component of the job.


List the key accomplishments and skills that must be achieved to be eligible for promotion to the next position, if any, on the career ladder.

Extensive experience with several different assay techniques.

Accurate recording and reporting of assay results.

Development of assay troubleshooting skills, both general and technique-specific

Demonstration of aptitude and interest in assay development.

Next position:  Research Associate


Four-year degree in a biological or physical science, with typical academic laboratory classes.

    • 0-3 years experience in biological or chemical laboratory work.

    • Knowledge and experience in lab processes and procedures.  Experience with cell culture sterile technique is preferred.

Skills and Experience

The Skills and Experience match parameters for the candidate are parsed from the Duties, Skills, and Education.

We are an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, or any other characteristic protected by law.

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We treat rare diseases, and that gives us rare opportunities. Chris Brodeur, Director, Corporate Compliance
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