Senior Manager, PMO
Location Cork, Ireland Workstyle Hybrid ApplyWho We Are
BioMarin is a global biotechnology company that relentlessly pursues bold science to translate genetic discoveries into new medicines that advance the future of human health.
Since our founding in 1997, we have applied our scientific expertise in understanding the underlying causes of genetic conditions to create transformative medicines, using a number of treatment modalities.
Using our unparalleled expertise in genetics and molecular biology, we develop medicines for patients with significant unmet medical need. We enlist the best of the best – people with the right technical expertise and a relentless drive to solve real problems – and create an environment that empowers our teams to pursue bold, innovative science. With this distinctive approach to drug discovery, we’ve produced a diverse pipeline of commercial, clinical and preclinical candidates that have well-understood biology and provide an opportunity to be first-to-market or offer a substantial benefit over existing therapeutic options.
About Technical Operations
BioMarin’s Technical Operations group is responsible for creating our drugs for use in clinical trials and for scaling production of those drugs for the commercial market. These engineers, technicians, scientists and support staff build and maintain BioMarin’s cutting-edge manufacturing processes and sites, provide quality assurance and quality control to ensure we meet regulatory standards, and procure the needed goods and services to support manufacturing and coordinating the worldwide movement of our drugs to patients.
Senior Manager PMO - Shanbally, Ringaskiddy, Cork
Hybrid Role: 3-4 days per week onsite
Closing date: 12 March 2026
The Senior Manager PMO plays a key role in the management of project delivery at the Shanbally site and reports to the Head of Site Projects. The Senior Manager PMO will be accountable for a central portfolio, responsible for governance, performance and capacity planning.
This position is responsible for developing, refining, and upholding project management standards, coordinating governance forums, and assisting with prioritisation, approval and execution across the site's project portfolio. The PMO Lead, intakes, develops and oversees improvement projects to ensure they are delivered according to the approved scope, budget, timeline, and business goals. Additionally, this role provides administrative support, monitors and reports on progress, and facilitates workshops focused on developing business cases and planning project implementation strategies.
The PMO Lead supports monthly Products & Projects Reviews by integrating project demand, capacity, and risks into site planning. This role links portfolio planning with project execution, oversees governance and risk management, ensures project alignment with strategy, manages dependencies, and tracks metrics for informed decisions.
Key Accountabilities:
- Project & Portfolio Management.
- Oversee projects from intake to benefits realisation.
- Support Project Managers, Risk Management, and Operational Readiness Plan
- (ORP) activities.
- Categorise project demand and ensure proper intake processes.
- Align projects with strategic, operational, compliance, and capacity priorities.
- Shape, Lead and Standardise the ORP model, incorporating end to end planning and execution from construction and IOQ completion through validation, regulatory readiness and initial commercial manufacturing.
- Prepare and present dashboards tracking status, risks, and escalations.
- Drive portfolio level planning, scheduling and governance processes.
- Develop and optimise PMO processes.
- Drive lessons learned and continuous improvement into project governance processes to refine future projects and ORP’s.
- Drive timely decisions to meet schedule and financial targets.
Planning & Governance:
- Develop and deploy PMO planning and governance processes onsite. Ensure clear reporting of project risks, dependencies, and constraints to the IBP forum and site risk register.
Products & Projects Review (P&PR):
- Join the monthly Products & Projects Review to share project updates and highlight any risks or issues to relevant stakeholders.
- Support the assessment of new project demand, capacity requirements, and resource availability.
Integration & Decision Support:
- Provide consolidated project status and risk inputs to the Head of Site Projects for Integrated Reconciliation Process and Management Business Review.
- Ensure that trade-offs impacting capacity, cost, service, or timelines for assigned projects are clearly documented and communicated.
Resource, Risk & Dependency Management:
- Collaborate with functional leaders to balance project resource requirements with operational priorities and limitations.
- Ensure clear oversight of critical path tasks, project interdependencies, and appropriate mitigation measures for assigned projects and initiatives.
Stakeholder Engagement:
- Engage with site flow teams, other cross-functional teams and departmental teams to ensure alignment through a standard process, resolve issues, and drive project delivery.
- Prepare and present project status, risks, and decision requirements to the Head of Projects and Site leadership team as required.
Key Interfaces:
- Head of Site Projects
- Integrated Business Planning Lead
- Senior Portfolio Manager, Capital Projects
- Finance (planning, governance)
- Leaders: Supply Chain, MFG Ops, Engineering, EHS, Quality, etc.
- Risk management
- Project Teams (development, execution)
Key Inputs & Outputs
Inputs:
- Requests for new project investments (capital and operational expenditures)
- Comprehensive business cases
- Budget proposals, phased planning, and resource capacity metrics
- Project details and risk assessments
- Strategic objectives and operational priorities
Outputs:
- Managed and prioritised project execution strategies for assigned projects, maintaining clear status, risk, and decision visibility.
- Key inputs to support business planning with comprehensive action tracking
- Assured outcome realisation
Qualifications:
- Education: Bachelor’s degree in Engineering, Science, Business, or Information Systems.
- Experience: 10+ years in project management or business process improvement within a GMP-regulated manufacturing environment.
- Prior PMO Experience Preferred
Key Competencies
- Ability to work effectively in cross-functional teams within a matrix organisation.
- Understanding of biopharma manufacturing processes, compliance and safety requirements.
- Strong financial and business acumen, with the ability to communicate complex information clearly to senior leaders.
- Demonstrated expertise in project and capital portfolio management, with a proven ability to identify, develop, and present key metrics in an industry-leading format.
- Solid governance, financial discipline, and execution focus.
- Strong communication and influencing skills.
Note: This description is not intended to be all-inclusive, or a limitation of the duties of the position. It is intended to describe the general nature of the job that may include other duties as assumed or assigned.
Equal Opportunity Employer/Veterans/Disabled
An Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability.
Equal Opportunity Employer/Veterans/Disabled
An Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability.