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Senior Research Associate II (TEMPORARY)

Location San Rafael, California
BioMarin is the world leader in delivering therapeutics that provide meaningful advances to patients who live with serious and life-threatening rare genetic diseases. We target diseases that lack effective therapies and affect relatively small numbers of patients, many of whom are children. These conditions are often inherited, difficult to diagnose, progressively debilitating and have few, if any, treatment options. BioMarin will continue to focus on advancing therapies that are the first or best of their kind.

BioMarin’s Research & Development group is responsible for everything from research and discovery to post-market clinical development. Research & Development involves all bench and clinical research and the associated groups that support those endeavors. Our teams work on developing first-in-class and best-in-class therapeutics that provide meaningful advances to patients who live with rare diseases. Come join our team and make a meaningful impact on patients’ lives. 

Duties


Purification of tagged and untagged proteins from bacterial and mammalian sources


Characterization of purified proteins using a variety of analytical tools


Perform purification methods as multiple scales, including using high-flow equipment


Design, execute, interpret experimental results with documenting work in ELN


Prepare slides, propose solutions and present results at project team meetings


Identify and implement new technologies or improved approaches in protein sciences

Skills


Protein purification utilizing Akta Pure and Avant platforms.


Experience performing ultrafiltration/diafiltration (TFF), and clarification processes.


Familiar with Unicorn  and ChemStation instrument software.


Analytical protein biochemistry methodology--SDS-PAGE, Western Blotting, ELISA, spectrophotometry are required.  Other analytical techniques such as capillary electrophoresis, HPLC, are highly desired.


Experience with robotics and other high throughput technologies to accelerate discovery and development is a plus.


Education


Bachelor’s degree in Biology or a related scientific field and at least 6-8 years of relevant experience or Master's degree with at least 4-6 years of relevant experience



We are an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, or any other characteristic protected by law.

About our location

San Rafael

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We treat rare diseases, and that gives us rare opportunities. Chris Brodeur, Director, Corporate Compliance
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