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Scientist I (TEMPORARY)

Location San Rafael, California
BioMarin is the world leader in delivering therapeutics that provide meaningful advances to patients who live with serious and life-threatening rare genetic diseases. We target diseases that lack effective therapies and affect relatively small numbers of patients, many of whom are children. These conditions are often inherited, difficult to diagnose, progressively debilitating and have few, if any, treatment options. BioMarin will continue to focus on advancing therapies that are the first or best of their kind.

BioMarin’s Research & Development group is responsible for everything from research and discovery to post-market clinical development. Research & Development involves all bench and clinical research and the associated groups that support those endeavors. Our teams work on developing first-in-class and best-in-class therapeutics that provide meaningful advances to patients who live with rare diseases. Come join our team and make a meaningful impact on patients’ lives. 

Duties




The Analytical Biochemistry and Cell Biology group within the Research department of BioMarin Pharmaceutical is seeking an exceptional individual at the Technical Scientist/Scientist level to conduct biochemistry and cell based research. Successful candidates will join a matrix-based department to develop and implement biochemical assays, cell-based disease models, and contribute to project teams. Applicants should have a PhD with expertise in cell based model systems. Direct hands on experience in cell culture and molecular biology techniques is required. Ability to work collaboratively on project teams, being resourceful, taking initiative, and attention to detail are essential. Candidates should be scientifically flexible in working in a variety of disease areas as business needs change.

Skills


RESPONSIBILITIES


-Cell culture based assays and disease models – understanding/testing disease mechanism, therapeutic testing, and migration/proliferation/activation assays.


-Molecular biology – qPCR, ELISA, Westerns, multiplex assays.



EXPERIENCE



Required Skills:


-PhD degree with extensive experience in cell culture and molecular biology techniques.


-Focused education on developing and implementing cell based models of disease.


-Human and mouse cell culture experience.


-Molecular biology – RNA isolation, qPCR, ELISA, Western, immunofluorescence.


-Strong organizational and computer skills.



Desired Skills:


-Experience with diseased mouse models a plus.


-Having mass spectrometry experience a plus.


-Having glycobiology experience a plus.



EQUIPMENT


Laboratory equipment.



CONTACTS


Must be able to work in a cross-discipline team-based format and present data at internal group and departmental meetings.

Education


Technical Scientist/Scientist 1:  PhD with 0-2+ years of relevant industry experience.



We are an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, or any other characteristic protected by law.

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