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Sr / Scientific Manager – Genetic Models In Vivo Program

Location San Rafael, California
BioMarin is the world leader in delivering therapeutics that provide meaningful advances to patients who live with serious and life-threatening rare genetic diseases. We target diseases that lack effective therapies and affect relatively small numbers of patients, many of whom are children. These conditions are often inherited, difficult to diagnose, progressively debilitating and have few, if any, treatment options. BioMarin will continue to focus on advancing therapies that are the first or best of their kind.

BioMarin’s Research & Development group is responsible for everything from research and discovery to post-market clinical development. Research & Development involves all bench and clinical research and the associated groups that support those endeavors. Our teams work on developing first-in-class and best-in-class therapeutics that provide meaningful advances to patients who live with rare diseases. Come join our team and make a meaningful impact on patients’ lives.

We are seeking an experienced Scientific Manager with a strong background and understanding of genetic engineering of rodent models, experience with vivarium and animal program (IACUC) administration, and experience in in vivo bio methods.  The successful candidate will serve as the centralized single point of contact and resident expert in the procurement, production, tracking and project management of all rodent colonies used for research and early development and assist in project management of animal program functions (IACUC support, training, document tracking).   This candidate should have a strong understanding of genetics and genetic modification methods (Transgenics, vector mediated knockout/knock in/knockdown, CRISPR), characterizing animal models, experience with the breeding and tracking of rodent colonies, and experience with animal program functions (IACUC function and administration).

The person in this role will:

  • Work with BioMarin Research teams and outside collaborators to identify and obtain animal models
  • Work with geneticists in creating animal models of human disease.
  • Coordinate with internal Research teams to provide timelines and resource availability projections in support of early-stage research.
  • Collaborate with various internal legal and business groups to establish contracts and ensure payments.
  • Establish and maintain a colony management tool to provide real time data for colony breeding and production in line with project needs.
  • Collaborate with Vivarium staff in the creation of SOP’s and policies, processes, and assist with various services in the new vivarium, as needed.
  • Assist with animal program training needs (IACUC and Bio methods training)
  • Work with the IACUC committee and vivarium staff to coordinate meetings, track animal protocols, facilitate facility inspections, prepare reports, and help maintain regulatory compliance

Required Skills/Experience:

  • Experience in the management and tracking of rodent colonies, project management certification a plus
  • Experience in the design and production of mutant mouse models of human disease
  • Strong genetics background as it relates to etiology of disease and integrative physiology (experience or academic training), scientific design experience a plus
  • Hands-on as well as training experience in handling, dosing, blood sampling and tissue harvest in rodents
  • Familiarity and/or experience with vivarium and animal program management, experience preferred with either AALAS technician certification and/or CPIA certification a plus
  • Ability to easily work on several projects simultaneously
  • Excellent verbal and written communication skills in the English language.
  • Highly collaborative and agile in nature
  • Ability to work toward established goals without daily supervision
  • Excel at organizing and tracking
  • Absent a Medical or Religious reason that prohibits vaccinations, all our incoming employees must be vaccinated

Absent a Medical or Religious reason that prohibits vaccinations, all our incoming employees must be vaccinated

We are an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, gender, gender identity, sexual orientation, national origin, disability status, protected veteran status, or any other characteristic protected by law.





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San Rafael


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We treat rare diseases, and that gives us rare opportunities. Chris Brodeur, Director, Corporate Compliance
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