Intern - Translational BiologyLocation San Rafael, California Apply
BioMarin is the world leader in delivering therapeutics that provide meaningful advances to patients who live with serious and life-threatening rare genetic diseases. We target diseases that lack effective therapies and affect relatively small numbers of patients, many of whom are children. These conditions are often inherited, difficult to diagnose, progressively debilitating and have few, if any, treatment options. BioMarin will continue to focus on advancing therapies that are the first or best of their kind.
The BioMarin Summer Internship Program will enable students to gain valuable experience and knowledge of the processes and systems within BioMarin, while gaining an insight into the pharmaceutical/biotech industry.
The mission of Translational Biology is to conduct preclinical translational research evaluating potential therapeutics for severe rare diseases with unmet medical needs. We help provide proof-of-concept preclinical data in relevant disease models and data for understanding of mechanisms of action for these potential therapeutics.
Research summer intern will work on 1 major project and 1 minor project over the 3-month internship. The successful candidate will partner closely with a team of scientists from translation biology, and other functional groups within BioMarin. The Intern will primarily be responsible for executing in vitro, and ex vivo studies to assess biodistribution, pharmacokinetics, efficacy and mechanism of action of potential therapeutics.
The responsibilities of the candidate are to:
- Make protein lysates and DNA and RNA from cells and tissues
- Determine target expression by varies methods, including but not limited to flow cytometry, droplet digital PCR or western blot
- Perform immunohistochemistry and in situ hybridization assays
- Perform basic histologic techniques, including but not limited to: fixation, embedding, sectioning, and staining
- Notebook keeping, compilation of data and interpretation into power point presentations
- Applicants should be at least in their 3rd or 4th year obtaining a BA/BS in Biochemistry, Molecular Biology, or Genetics. MS are also encouraged to apply.
- Strong performance in relevant academic courses in is required. Candidates with previous laboratory experience in protein/DNA/RNA purification, PCR, westerns, and/or immunohistochemistry/microscopy will be preferred.
- The position requires self-motivation, teamwork, and dedication to quality in a fast-paced scientific setting.
- Student must be returning to school in the Fall Term OR has graduated within the 1 year of the start of the intern program
- Must be available to work 40 hours a week
- Housing and Transportation is responsibility of the Intern
Benefits of a BioMarin Internship:
- Apply skills and knowledge learned in the classroom to on-the-job experiences
- Comprehensive, value-added project(s)
- Work in teams and with colleagues in a professional environment
- Develop technical skills specific to your major
- Provides opportunities for professional development by building relationships and learning about other parts of the business
- Weekly lunch seminar series with Executive Staff
- End of summer poster presentation to the BioMarin Community
We are an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, or any other characteristic protected by law.