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Research Associate

Location Novato, California


BioMarin is the world leader in delivering therapeutics that provide meaningful advances to patients who live with serious and life-threatening rare genetic diseases. We target diseases that lack effective therapies and affect relatively small numbers of patients, many of whom are children. These conditions are often inherited, difficult to diagnose, progressively debilitating and have few, if any, treatment options. BioMarin will continue to focus on advancing therapies that are the first or best of their kind. 

BioMarin’s Technical Operations group is responsible for creating our drugs for use in clinical trials and for scaling production of those drugs for the commercial market. These engineers, technicians, scientists and support staff build and maintain BioMarin’s cutting-edge manufacturing processes and sites, provide quality assurance and quality control to ensure we meet regulatory standards, and procure the needed goods and services to support manufacturing and coordinating the worldwide movement of our drugs to patients. Come join our team and make a meaningful impact on patients’ lives.

The selected candidate will work in the Formulation Development group to assist in the advancement of BioMarin’s therapeutics for clinical evaluation and potential commercialization.  The candidate will be responsible characterization drug products, screening of formulation prototypes, evaluating product stability and compatibility with various container closure systems using routine and semi-routine analytical methods under limited supervision.  The selected candidate should possess excellent analytical, organizational and communication skills and be a self-starter willing to work efficiently and collaboratively in a dynamic environment.


Perform routine and semi-routine analysis of drug product formulations using chromatographic (reverse phase, size exclusion and ion exchange HPLC), spectrophotometric (UV, CD, florescence), calorimetric (DSC, ITC), microscopy and standard wet chemistry techniques.

Evaluate stability of various solid and liquid formulation prototypes using relevant assays

Plan and execute experimental studies in an efficient manner to meet project goals and timelines

Provide concise and quantitative analysis of data and interpretation of experimental results.

Provide effective oral presentations at department and interdepartmental meetings

Write experimental protocols and technical reports summarizing development work

Maintain good and timely documentation of experiments

Adhere to Good Laboratory Practices and SOPs


B.S. or M.S in the Pharmaceutical Sciences, Biochemistry, Biophysical Chemistry or related discipline


0- 2 years of relevant work experience

Fully proficient in fundamental laboratory techniques and equipment

Ability to efficiently plan, design and execute experiments under limited supervision

Excellent oral and written communication skills

Knowledge of analytical techniques—HPLCs, calorimetry, spectrophotometry, light scattering, Freeze Drying Microscopy, Karl Fisher, pH, Osmolality—used for drug product screening/characterization is preferred.

Experience with formulation development activities (pH profiling, excipient/formulation prototype screening, compatibility evaluation of drug product with fill-finish processing materials and container closure components, managing stability programs) is highly desirable.

We are an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, or any other characteristic protected by law.

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We treat rare diseases, and that gives us rare opportunities. Chris Brodeur, Director, Corporate Compliance
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