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Sr Scientist 1, Neuroscience, Biology Research

Location San Rafael, California
BioMarin is the world leader in delivering therapeutics that provide meaningful advances to patients who live with serious and life-threatening rare genetic diseases. We target diseases that lack effective therapies and affect relatively small numbers of patients, many of whom are children. These conditions are often inherited, difficult to diagnose, progressively debilitating and have few, if any, treatment options. BioMarin will continue to focus on advancing therapies that are the first or best of their kind.

BioMarin’s Research & Development group is responsible for everything from research and discovery to post-market clinical development. Research & Development involves all bench and clinical research and the associated groups that support those endeavors. Our teams work on developing first-in-class and best-in-class therapeutics that provide meaningful advances to patients who live with rare diseases. Come join our team and make a meaningful impact on patients’ lives.

Sr Scientist 1, Neuroscience / Biology Research

BioMarin seeks a motivated, capable, creative and team-oriented scientist to support Research & Development in generating therapeutics to treat genetic neurological disorders. Research & Development involves all bench and clinical research and the associated groups that support those endeavors. Our teams work on developing first-in-class and best-in-class therapeutics that provide meaningful advances to patients who live with genetic disorders. The scientist will be working closely with Neuro Therapeutic Area leads in R&D to drive, coordinate and advance multiple early stage programs and technologies. Attention to detail, cooperativity towards ensuring solid science, and agility are some of the qualities we are looking for to ensure fit with BioMarin’s goals and ideals in order to drive rapid success as we tackle serious and often life-threatening diseases. Thought contributions on new indications and technology to feed the pipeline are welcome and encouraged.

Primary Responsibilities

The scientist will manage multiple research projects within the Neuro therapeutic area space at BioMarin. This entails coordinating with our external collaborators and partners, communicating effectively across disciplines and departments, organizing and tracking project resources and timelines, as well as assisting in the design of critical experiments with subject matter experts. The candidate is expected to add their own subject matter expertise in the field of iPSCs with specialization in establishing induced neuron culture systems and technologies to complement the existing internal and external scientific community at BioMarin. In addition to this leadership role, as a member of the Model Development group in Biology Research, the scientist will be expected to contribute, not just in helping to translate in vitro and in vivo studies but to also assist with animal study designs and execution on occasion.

Required Experience:

  • Ph.D. in neuroscience, cellular biology or a closely related field
  • 5 years of relevant scientific team managerial experience, especially in industry
  • Strong publication record and example of ability to obtain independent funding
  • Proficient in cell culture and quality control of culture systems including successful at using iPSC cell systems or establishing robust primary cells for use as screening and translational biology tools in neuroscience.
  • Track record of using current and emerging cellular technologies including CRISPR gene editing, mixed neuronal cultures, and improved protocols
  • Organized with exceptional writing skills and ability to analyze and communicate data objectively is essential, document findings accurately and compose reports in a concise and highly organized fashion.
  • Technical expertise in designing and working with genetic animal models of neurological disease, experience submitting IACUC protocols, and able to be hands on and contribute alongside a team of RAs and technical scientists
  • Absent a Medical or Religious reason that prohibits vaccinations, all our incoming employees must be vaccinated

Successful candidate attributes:

  • Prior work with oligonucleotides, AAV gene therapy, or other therapeutic modalities in the CNS a plus.
  • Comfortable in a dynamic, ambitious and hard-working environment
  • Able to positively influence a cross-functional team of non-direct reports
  • Excellent presentation skills and expected to present frequently to multiple audiences
  • Objective under pressure; savvy

We are an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, gender, gender identity, sexual orientation, national origin, disability status, protected veteran status, or any other characteristic protected by law.

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We treat rare diseases, and that gives us rare opportunities. Chris Brodeur, Director, Corporate Compliance
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