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Scientist II / Senior Scientist - Vector Biology, Muscle Gene Therapy

Location San Rafael, California
BioMarin is the world leader in delivering therapeutics that provide meaningful advances to patients who live with serious and life-threatening rare genetic diseases. We target diseases that lack effective therapies and affect relatively small numbers of patients, many of whom are children. These conditions are often inherited, difficult to diagnose, progressively debilitating and have few, if any, treatment options. BioMarin will continue to focus on advancing therapies that are the first or best of their kind.

BioMarin’s Research & Development group is responsible for everything from research and discovery to post-market clinical development. Research & Development involves all bench and clinical research and the associated groups that support those endeavors. Our teams work on developing first-in-class and best-in-class therapeutics that provide meaningful advances to patients who live with rare diseases. Come join our team and make a meaningful impact on patients’ lives. 

The Vector Biology Group at BioMarin Pharmaceutical is currently recruiting exceptional individuals at the Scientist level in our research- Vector Biology group to specialize in DMD – gene therapy research. Successful candidates will join a dynamic interdisciplinary group which will develop and commercialize the major gene therapeutics for several genetic diseases. Applicants should have a PhD degree in a relevant field, be experts in DMD biology, molecular biology, and cell biology. Experience in cell culture and molecular biology techniques, viral-based vector biology, virology, gene therapy, protein expression analysis is required. Teamwork, individual-initiative, and meticulous recordkeeping are essential.

SUMMARY

This position is for a research scientist with expertise in gene therapy and the biology of Duchenne Muscular Dystrophy.

RESPONSIBILITIES

-Muscle applications/diseases, assays

-Cell culture based assays and vector production

-Molecular biology – cloning, sequence analysis, PCR, qPCR

-Execute and document laboratory procedures and experiments with great attention to detail

EXPERIENCE

Required Skills:

Minimum Required:

-PhD degree with extensive experience in cell culture and molecular biology techniques.

-Muscle biology experience, in vitro and in vivo experience.

-Gene therapy experience

-Cell culture work – multiple cell lines, viral production

-Molecular biology – DNA isolation, primer design, PCR, cloning techniques

-Strong organization skills and computer skills.

Desired Skills:

-Assay development experience

-Protein biology/ chemistry – ELISA, Western

-Strong organization skills and ability to multitask efficiently in a dynamic environment

EDUCATION

Scientist 2: PhD with 2-5+ years relevant industry experience

Senior Scientist 1: PhD with 5+ years relevant industry experience

EQUIPMENT

Laboratory equipment

CONTACTS

Must be able to work in a team format and present data at internal meetings.

SUPERVISOR RESPONSIBILITY

No directs reports.



We are an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, or any other characteristic protected by law.

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