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Scientist 1, Cardiovascular Research

Location San Rafael, California Workstyle Open to Hybrid
BioMarin is the world leader in delivering therapeutics that provide meaningful advances to patients who live with serious and life-threatening rare genetic diseases. We target diseases that lack effective therapies and affect relatively small numbers of patients, many of whom are children. These conditions are often inherited, difficult to diagnose, progressively debilitating and have few, if any, treatment options. BioMarin will continue to focus on advancing therapies that are the first or best of their kind.

BioMarin’s Research & Development group is responsible for everything from research and discovery to post-market clinical development. Research & Development involves all bench and clinical research and the associated groups that support those endeavors. Our teams work on developing first-in-class and best-in-class therapeutics that provide meaningful advances to patients who live with rare diseases. Come join our team and make a meaningful impact on patients’ lives.

The Biology Research department is seeking to hire a highly motivated individual at the Scientist level to work on an early-stage in vivo research team, evaluating potential therapeutics for cardiovascular indications. The ideal candidate would provide analytical histology support to several cardiovascular gene therapy studies, and will work independently to develop and optimize analytical strategies for preclinical in vivo study evaluation. Applicants should have experience in basic histologic techniques, immunohistochemical and in situ hybridization assays, imaging and confocal microscopy. Experience developing immunohistochemistry assays, automated image acquisition and quantitative image analysis is required. The ideal candidate is highly motivated, tech savvy, a critical thinker, and able to work both independently as well as in a team environment. In addition, the candidate should possess excellent analytical, organizational and communication skills.

Responsibilities:

• Developing and performing immunohistochemical and in situ hybridization assays
• Performing basic histologic techniques (including but not limited to): fixation, embedding, sectioning and staining• Epifluorescence and confocal microscopy
• Image analysis

• Technical support for imaging database, microscopes and autostainers.
• Execute and document laboratory procedures and experiments with great attention to detail.
• Perform general lab duties. Experience
• Experience with Microscopy –
epifluorescent, confocal, automated slide scanning
• Proficient with Image analysis software –
Visiopharm, ImageJ
• Good interpersonal, verbal and written communication skills.
• Proficiency in Microsoft Word,
Powerpoint, and Excel.

Education:

 - PhD plus 0-2+ years relevant industry experience - OR - Bachelor’s degree and at least 10 years of experience - OR - Master’s degree with at least 8 years of relevant experience.


PLEASE NOTE: Absent a Medical or Religious reason that prohibits vaccinations, all our incoming employees must be vaccinated for COVID-19.

We are an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, gender, gender identity, sexual orientation, national origin, disability status, protected veteran status, or any other characteristic protected by law.

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We treat rare diseases, and that gives us rare opportunities. Chris Brodeur, Director, Corporate Compliance
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