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Research Associate 2, Capsid Engineering, Gene Therapy Research

Location :San Rafael, California

Workstyle :Onsite Only

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Overview

With accelerated review underway in the United States and Europe for our Hemophilia A drug, a second gene therapy program entering the clinic for PKU patients, and a third program in late research for Hereditary Angioedema, BioMarin continues to pioneer innovative approaches to treating rare diseases. Our commitment to gene therapy is further underscored by having developed the first and largest gene therapy manufacturing facility in the world. The scientific possibilities and the hope we offer to patients with rare diseases is enormous.

BioMarin is a midsize biotechnology company with a market cap of approximately 18 billion. Over the course of our 22 year history we have successfully launched 7 drugs for the treatment of rare diseases. Our success is due to our scientific rigor and our ability to leverage multiple therapeutic modalities. BioMarin is based in the San Francisco Bay Area and offers a comprehensive relocation program.

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Success Profile

Check out the traits we’re looking for and see if you have the right mix.

  • Decision Making
  • Influence
  • Collaboration
  • Agility
  • Leadership
  • Intellectual Curiosity

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Our CULTURE

  • Patient Focused
  • Results Oriented
  • Pioneering Science
  • Cross Functional Collaboration
  • Willing to try new ways to look at problems

Benefits

  • Healthcare

  • Medical

  • Dental

  • Vision

  • Health & Wellness Programs

  • 401(k)/Retirement plans

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" BioMarin has this, in their own DNA, an approach: they only work on projects for which they know the underlying biology."
Lon C., Chief Scientific Officer
"We’ve got to understand: What are the problems other people are trying to solve? And do we have a better way of fundamentally doing that?"
Brinda B, GVP, Corporate and Business Development

Responsibilities

Who We Are

For more than two decades, going our own way has led to countless breakthroughs, bettering the lives of those suffering from rare genetic disease. In 1997 we were founded to make a big difference in small patient populations. Now we seek to make an even greater impact by applying the same science-driven, patient-forward approach that propelled our last 25 years of drug development to larger genetic disorders, as well as genetic subsets of more common conditions. Through our unparalleled expertise in genetics and molecular biology, we will continue to develop targeted therapies that address the root cause of the conditions we seek to treat. Applying our knowledge to make a transformative impact is not just a calling, but an obligation to those who will benefit most. The end goal has always been better lives and now we can reach more.

And the more people we reach, the more our impact can grow. We transform lives through genetic discovery.

Our Culture

Our desire to make a positive impact on our patients extends to our employees and BioMarin is committed to fostering an inclusive environment where every person feels seen, valued, and heard – so employees can thrive in all areas of their lives, in and outside of work. We seek to provide an open, flexible, and friendly work environment to empower people and to provide them with the ability to develop their long-term careers. Ultimately, we want to be an organization where people enjoy coming to work and take pride in our efforts to help patients.

BioMarin’s Research & Development group is responsible for everything from research and discovery to post-market clinical development. Research & Development involves all bench and clinical research and the associated groups that support those endeavors. Come join our team and make a meaningful impact on patients’ lives.

We are seeking to hire a Research Associate - 2 for our AAV Capsid Engineering Team under Gene Therapy Research. We are looking for a highly motivated and diligent multitasker who has a great appetite to learn and grow in gene therapy research. The role will be responsible for assisting on projects by performing experiments that enable the development and use of next-generation AAV capsids for Gene Therapy. The successful candidate will have a background in biological science with hands-on experience in molecular biology, mammalian cell culture, AAV production and analytical assays.

Responsibilities

  • Perform AAV virus production as well as AAV analytical assays
  • Design and clone DNA constructs and perform in vitro transduction assays as needed for projects.
  • Perform standard molecular biology techniques such as DNA, RNA extractions from mammalian cell culture or mice/NHP tissues, PCR, RT/qPCR as needed for projects.
  • Maintain detailed electronic laboratory notebook to record the day-to-day activities including experimental protocols and data generated.
  • Present data in meetings.
  • Effectively communicate and collaborate with team members within the research group as well as cross-functional research groups.

Skills

  • Experience working with AAVs is desired.
  • Hands-on experience with mammalian cell culture is desired.
  • Experience performing AAV virus production as well as AAV analytical assays are desired.
  • Experience on molecular biology methods not limited to PCR, RT/q-PCR, molecular cloning, DNA/RNA extractions from mammalian cell culture/mice/NHP are desired.
  • Open to learning new skills and techniques as needed to succeed in the assigned tasks.
  • Ability to take on multiple tasks and work in a fast-paced environment.
  • Good interpersonal as well as scientific communication and written skills for presentations and record maintenance.

Education & Experience

  • Bachelor’s degree preferably in Biology or Chemistry with at least 4 years of experience; Master’s degree with at least 2 years of relevant experience

PLEASE NOTE: Absent a Medical or Religious reason that prohibits vaccinations, all our incoming employees must be vaccinated for COVID-19.

We are an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, gender, gender identity, sexual orientation, national origin, disability status, protected veteran status, or any other characteristic protected by law.
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About our location

San Rafael

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Our Benefits

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Meet Our Team

From internationally renowned scientists to patient advocates, BioMarin Hemophilia has brought together the right people.

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In the News

BioMarin has entered into a preclinical collaboration and license agreement with DiNAQOR, a gene therapy platform company, to develop novel gene therapies to treat rare genetic cardiomyopathies.

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