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Research Associate II (TEMPORARY)

Location Novato, California
BioMarin is the world leader in delivering therapeutics that provide meaningful advances to patients who live with serious and life-threatening rare genetic diseases. We target diseases that lack effective therapies and affect relatively small numbers of patients, many of whom are children. These conditions are often inherited, difficult to diagnose, progressively debilitating and have few, if any, treatment options. BioMarin will continue to focus on advancing therapies that are the first or best of their kind.

BioMarin’s Technical Operations group is responsible for creating our drugs for use in clinical trials and for scaling production of those drugs for the commercial market. These engineers, technicians, scientists and support staff build and maintain BioMarin’s cutting-edge manufacturing processes and sites, provide quality assurance and quality control to ensure we meet regulatory standards, and procure the needed goods and services to support manufacturing and coordinating the worldwide movement of our drugs to patients. Come join our team and make a meaningful impact on patients’ lives. 

Duties


DESCRIPTION


BioMarin is the world leader in delivering therapeutics that provide meaningful advances to patients who live with serious and life-threatening rare genetic diseases. We target diseases that lack effective therapies and affect relatively small numbers of patients, many of whom are children. These conditions are often inherited, difficult to diagnose, progressively debilitating and have few, if any, treatment options. BioMarin will continue to focus on advancing therapies that are the first or best of their kind.

BioMarin’s Technical Operations group is responsible for creating our drugs for use in clinical trials and for scaling production of those drugs for the commercial market. These engineers, technicians, scientists and support staff build and maintain BioMarin’s cutting-edge manufacturing processes and sites, provide quality assurance and quality control to ensure we meet regulatory standards, and procure the needed goods and services to support manufacturing and coordinating the worldwide movement of our drugs to patients. Come join our team and make a meaningful impact on patients’ lives. 



SUMMARY DESCRIPTION


The selected candidate will work in the Analytical Chemistry group to assist in the advancement of BioMarin’s therapeutics for clinical evaluation and potential commercialization. The candidate will be responsible for developing analytical methods and performing the work required for transfer of these methods to assay service groups in Analytical Chemistry and to the Quality Control group. The selected individual will work within Analytical Chemistry’s Vector Biology and Immunochemistry team.  The selected candidate should possess excellent analytical, organizational and communication skills and be a self-starter willing to work efficiently and collaboratively in a dynamic environment.



RESPONSIBILITIES



    • Operate fundamental laboratory equipment required for cell and molecular biology.

    • Efficiently plan, design, and execute experiments under limited supervision.

    • Maintain excellent laboratory notes.

    • Communicate research results in oral and written formats.

    • Design and execute analytical techniques— qPCR, ddPCR, ELISA, fluorescence, colorimetric, chemiluminescence microplate assays, protein-protein interaction methods, protein and nucleic acid gel electrophoresis, western blotting, immunofluorescence and other cell-based detection methods, flow cytometry.

    • Execute cell-based assays, viral


Skills



    • At least 2 years of relevant experience or minimal experience with Masters desired.

    • Fully proficient in fundamental laboratory techniques and equipment.

    • Ability to efficiently plan, design and execute experiments under limited supervision.

    • Proven data analysis skills.

    • Excellent oral and written communication skills within cross-functional environment.

    • Excellent cell culture skills for bacterial and human cell lines.

    • Knowledge of analytical techniques – PCR, qPCR, ddPCR, ELISA, fluorescence, colorimetric, chemiluminescence microplate assays, protein-protein interaction methods, protein and nucleic acid gel electrophoresis, western blotting, immunofluorescence and other cell-based detection methods, flow cytometry.

    • Experience with transformation of bacteria and clone isolation and characterization.

    • Experience with RNA, DNA, and protein isolation, purification, and evaluation methods required.

    • Experience with viral and cell-based assays desired.

    • Experience with automation desired.



    • Proven flexibility and execution skills to deliver in a fast-paced, multi-tasking environment.


Education





  • B.S. or M.S. in Biology, Molecular Biology, Cell Biology, Biochemistry, Virology, or related discipline.


We are an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, or any other characteristic protected by law.

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