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Research Associate 1

Location Novato, California
BioMarin is the world leader in delivering therapeutics that provide meaningful advances to patients who live with serious and life-threatening rare genetic diseases. We target diseases that lack effective therapies and affect relatively small numbers of patients, many of whom are children. These conditions are often inherited, difficult to diagnose, progressively debilitating and have few, if any, treatment options. BioMarin will continue to focus on advancing therapies that are the first or best of their kind.

BioMarin’s Technical Operations group is responsible for creating our drugs for use in clinical trials and for scaling production of those drugs for the commercial market. These engineers, technicians, scientists and support staff build and maintain BioMarin’s cutting-edge manufacturing processes and sites, provide quality assurance and quality control to ensure we meet regulatory standards, and procure the needed goods and services to support manufacturing and coordinating the worldwide movement of our drugs to patients. Come join our team and make a meaningful impact on patients’ lives. 


The selected Research Associate will support the formulation development activities of novel molecules (proteins, enzymes, virus-like particles) in early-stage clinical development. Formulation development activities include stability testing and characterization of routes of degradation in liquid and solid state formulations under a variety of real time, accelerated and physical stress conditions.

Candidate will work under general supervision of a manager and support in the design and execution formulation development studies. Candidate will make detailed observations, analyze data, and interpret/present results.   The prospective Individual should be familiar with and be able to follow Standard Operating Procedures (SOPs) for experimental operation and data recording.

This is a laboratory-based position and the candidate must be familiar with laboratory operations (weighing chemicals, balance operation, pH measurement, buffer preparation, lab safety). Familiarity with analytical techniques including PCR and liquid chromatography is a plus


The prospective employee will work in the Formulation Development group to assist in the advancement of BioMarin’s therapeutics for clinical evaluation and potential commercialization. The candidate will be responsible characterization drug products, screening of formulation prototypes, evaluating product stability and compatibility with various container closure systems using routine and semi-routine analytical methods under limited supervision. The selected candidate should possess excellent analytical, organizational and communication skills and be a self-starter willing to work efficiently and collaboratively in a dynamic environment. Activities included, but not limited to be:

  • Preparation of assay reagents and buffers.
  • Perform routine and semi-routine analysis of drug product formulations using chromatographic (reverse phase, size exclusion and Ion exchange HPLC), spectrophotometric (UV-VIS, florescence), and standard wet chemistry techniques.
  • Familiarity with nucleic acid quantification techniques such as qPCR or ddPCR
  • Learn and Perform analysis of data and interpretation of experimental results
  • Prepare and deliver effective oral presentations at department and interdepartmental meetings
  • Maintain good and timely documentation of experiments
  • Contribute to and provide solutions to technical problems and think creatively.
  • Follow Test methods, and SOPs, policies, and regulations, and to perform routine lab equipment maintenance is required.


  • B.S. in the Pharmaceutical Sciences, Biochemistry, Biophysical Chemistry or related discipline


  • 2-5+ years of relevant laboratory experience in a pharmaceutical/R&D environment
  • Candidate should have a working knowledge of performing HPLC based experiments using Agilent Chemstation, Waters Empower or Thermo Chromeleon
  • Working knowledge of Microsoft Excel, Word, and PowerPoint.
  • Strong problem-solving, documentation and organizational skills with a focus on details and results.
  • Strong interpersonal, communication and presentation skills and the ability to thrive in a fast-paced dynamic environment.
  • Ability to work in a team environment.

We are an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, or any other characteristic protected by law.

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We treat rare diseases, and that gives us rare opportunities. Chris Brodeur, Director, Corporate Compliance
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