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Senior Scientist II Clinical Genomics

Location London, United Kingdom Workstyle Hybrid

Who We Are

From research and discovery to post-market clinical development, our WWRD engine involves all bench and clinical research and the associated groups that support those endeavors. Our teams work on developing first-in-class and best-in-class therapeutics that provide meaningful advances to patients who live with genetic diseases.

The Genomics team at BioMarin is seeking an Associate Director position in the Clinical Genomics team. The primary responsibilities of this role will be to oversee and guide the application of genetic and genomic tools in BioMarin’s clinical trials. This will require the candidate to have a strong scientific skillset, but also the ability to engage with the relevant clinical teams to ensure the right scientific questions are being asked in each trial and the right samples collected & data generated to answer them.
The successful candidate will actively represent Clinical Genomics on cross-functional project teams (e.g. with clinical, regulatory, commercial) and engage with key opinion leaders and external stakeholders. They will also be responsible for defining key scientific and operational questions and directing groups of contracted researchers and vendors to address these in line with clinical timelines. They will also work closely with pre-clinical programmes to anticipate potential opportunities for genomics to impact clinical and commercial success. The candidate will have a strong statistical genetics background with a deep understanding of the process of drug development. They will be familiar with cutting edge genomic techniques and their application in clinical trials. They will have a collaborative and collegial approach to working in a fast paced and exciting environment and be enthusiastic about developing novel approaches to using -omics data in a modern drug discovery pipeline.
  • Develop and apply genomic tools to drive patient selection in early and late stage therapeutic programmes
  • Independently drive research within larger multi-functional teams/context, and make decisions while adapting to non-scientific implications and feedback
  • Lead a team of contracted scientists to define key questions around business needs/timelines, develop scientific approach to address needs, and deliver insights within complex and high urgency timelines
  • Communicate and contextualise findings to wider business, external stakeholders, and health authorities to influence thinking internally and externally
  • Prepare study synopses, protocols, study reports and regulatory documents to support the development process
Required Experience:
  • PhD in statistical genetics or a related field and 5+ years of experience working in pharmaceutical industry
  • Established reputation and publication record in the field of statistical genetics
  • Experience independently leading complex research projects
  • Management experience of internal team members or teams of external contractors

Equal Opportunity Employer/Veterans/Disabled

An Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability. 

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